Deciphering the pathways for evaluation of nanotoxicity: Stumbling block in nanotechnology
نویسندگان
چکیده
Nanosafety has been a subject of scrupulous indagation attributed to the ambiguity in terms harmonizing and perceiving nano risk evaluation. Nanotoxicity is an emanate pigeonhole nanotechnology. The burgeoning commercial products grafted with engineered nanomaterials escalated exponentially. Inevitably, profile their repercussions on ecosystem mankind must be meticulously assessed. research fraternity evolve innovations prognosticate unsought nuisance that does not prevail yet frame reference nanotoxicity due proliferation utilization for consumers' product. Besides, it imperative contemplate whether size only characteristic matters detrimental impacts nanoscale materials. design development safe substantially drug discovery could benchmark. As safety assessment utmost importance, therefore pre-eminent lessen animal analysis by inception auxiliary or prognostic silico vitro methods which become precedence. To perceive paradigms nanotoxicity, this robust will provide comprehensive exploration clearance, kinetics, metabolism, mapping fate, physical properties toxicity nanomaterials. First, different characteristics linked toxicological effects presented. Accordingly, mechanism nanoparticles exhibit delineated aid nanoparticle redesign reduce impact. Second, overview physiochemical techniques biochemical methodologies adopted characterization testing screening Third, adverse impact human environment highlighted. Finally, challenging pathways significant strategies eradicate nanotoxocity addressed proffer solid rationale translating promises
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ژورنال
عنوان ژورنال: Cleaner engineering and technology
سال: 2021
ISSN: ['2666-7908']
DOI: https://doi.org/10.1016/j.clet.2021.100311